Category: Clinical Research

February 9, 2021
Research is good for the heart, blog, Older white male running in a race, heart disease clinical research

Around 655,000 Americans die every year from heart disease. It is the leading cause of death for men, women, and most ethnic groups in the U.S. February 2021 is the 57th anniversary of the American Heart Month initiative. In most cases, heart disease is preventable through healthier lifestyle changes. Also, during the month, fundraising events go toward clinical research efforts to improve the care of those with heart disease. Here are some tips that are good for the heart and what research is doing to help.

Love Your Heart 

African American doctor listening to heart and lungs of Asian patient, heart health, heart disease clinical trials

Amid the pandemic, many have adopted unhealthier lifestyles that raises their risk for heart-related conditions. Smoking, high blood pressure, and high cholesterol are key risk factors for heart disease. Diabetes, unhealthy diet, alcohol abuse, physical inactivity, and obesity are medical conditions and lifestyle choices that raise that risk. Here are changes you can make to keep your heart healthy:

  • Get 150 minutes of moderate physical activity a week.
  • Quit smoking and refrain from drinking too much alcohol.
  • Maintain a healthy weight.
  • Get regular checkups.
  • Control chronic conditions like diabetes, hypertension, high cholesterol.

Healthier living is a journey, but with the support of a community that drives heart-health, anything is possible. Get involved today by taking part in the 7 Days of Self Care initiative or other various events this month.

The Future of Heart Disease

Recently it was discovered that two newer classes of drugs used to treat Type 2 diabetes (SGLT2 inhibitors and GLP-1 RA medications) had been shown to protect patients against heart disease and chronic kidney disease. This means other groups such as people with heart failure with reduced ejection fraction with or without Type 2 diabetes and people with chronic kidney disease who do not have Type 2 diabetes could benefit from these types of medications.

Heart failure research, older Caucasian male with glasses, smiling, heart disease research.

Clinical research must continue so that we can ensure millions of people live longer and healthier. The donations raised and volunteers who participate in research studies make these advancements possible. To learn how you can get involved in one of our heart-related studies with us here at ActivMed Practices & Research, call our Methuen, MA location at (978) 655-7155. You can also view a listing of studies on our website.

References:

https://www.cdc.gov/heartdisease/american_heart_month.htm

https://www.heart.org/en/around-the-aha/february-is-american-heart-month

https://www.nhlbi.nih.gov/health-topics/education-and-awareness/american-heart-month/about

January 15, 2021
Diversity in COVID-19 research, pictures of 4 diverse people with masks

As we pass the first anniversary of the first reported case of COVID-19 in the U.S., a lot of uncertainty remains despite the tremendous progress. Diversity has been a challenge long before the coronavirus, and it’s vital to end the disproportionate impact in communities of color. As clinical research efforts continue to deliver new ways to detect, prevent, and treat COVID-19, study participants’ diversity will be more critical than ever.

Group of diverse people, diversity is important in clinical research

Importance of Diversity in Research

Genetics and biological makeup differ for every person. For vaccines, this means how antibodies are produced in one ethnic group can vary from others. Since the pandemic began, data gathered shows much higher rates of infection, hospitalization, and death in people of color.

Diversity also covers various age groups, gender, and backgrounds. Older individuals and those with underlying health conditions are more likely to suffer severe symptoms, hospitalizations, and death as well. The populations with the most significant risk stand to benefit the most from the new possibilities being developed for COVID-19. At the same time, they need to be tested in these groups to ensure they are safe and effective for everyone.

Disparity Causes

Historical mistreatment of minority populations in research studies fuels mistrust and prevents some from participating. Though safeguards, ethical laws, and oversight by the FDA have made research studies much safer, the past is still fresh in minds. Others feel they lack the tools to make it to appointments due to lack of transportation, inability to leave work early, childcare needs, and so on. The reality is that many studies offer options to help with those challenges, such as reimbursement for time and travel, transportation help, and extended hours.

By talking with the study office, you can learn more about the study, potential risks, and possible benefits. The commitment for each study varies. A vaccine study may last two years, while an antibody study may be  one visit for example. While there are criteria for each that must be met, flexibility of choice is always a bonus. Volunteering in clinical research studies is 100% voluntary throughout the entire process. You can end your commitment at any time in the event you cannot continue.

Rise up against COVID, participate in a research study

ActivMed Practices & Research is proud to be a part of history in the fight to end COVID-19. Our site participated in the large AstraZeneca vaccine study, as well as other antibody test studies. Get further details about enrolling COVID-19 studies here.

Without the selfless gift our volunteers offer, the progress made thus far wouldn’t be possible. To learn more about volunteering or view a current list of enrolling studies at each of our sites, visit our website.

References:

https://hub.jhu.edu/2020/11/30/diversity-covid-19-vaccine-trials/

https://www.forbes.com/sites/tracybrower/2020/05/19/diversity-equity-and-inclusion-what-the-coronavirus-teaches-and-how-we-must-respond/?sh=8f5aaf4d0534

https://www.henryford.com/blog/2020/11/diversity-in-vaccine-trials

https://www.clinicalresearchnewsonline.com/news/2020/10/27/why-diversity-matters-covid-19-and-the-search-for-a-vaccine

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